One-step immunochromatographic test for the detection of Entamoeba antigens in stool samples.
Entamoeba histolytica is the protozoan parasite responsible for dysentery and amebiasis. It is the third leading cause of morbidity and mortality due to parasitic disease in humans after malaria and schistosomiasis, and is estimated to be responsible for between 50000 and 100000 deaths every year.
In recent years, a new understanding of this organism has lead to the recognition that two species actually exist within what was previously known as E. histolytica. Of these two organisms E. histolytica is the pathogenic, causing all invasive disease while the other, E. dispar is non pathogenic, as it is not capable of invading tissue. The two species are morphologically identical, so although diagnosis is usually performed by microscopic examination, it can not differentiate them.
Simple Entamoeba and Stick Entamoeba tests use monoclonal antibodies specific for Entamoeba histolytica that detect all forms of the parasite during its life cycle.
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