One-step immunochromatographic test for the qualitative detection of GDH (Glutamate Dehydrogenase) from C.difficile in human faeces
A positive signal in the test indicates the presence of C.difficile in the stool sample. Subsequent analysis of the sample with a test for detecting C.difficile toxins (such as Operon's 2A-Bdiff test) confirms whether the strain is toxigenic and, therefore, pathogenic and disease-causing.
Some of the leading healthcare societies propose the use of a two-step protocol for identifying toxigenic C.difficile involving an initial screening of the sample with a GDH test and, if the result is positive, use of a second test to detect toxins from C.difficile as not all strains of this microorganism produce them.
Operon offers the possibility of following this protocol using its GDH and 2A-Bdiff tests.
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