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MAbs. MONOCLONAL ANTIBODIES


Since 1987, our R&D team has developed a wide range of hybridomas that are now being used for producing mouse monoclonal antibodies (mAbs).

Nowadays we have 7 bioreactors which can produce up to several hundreds of grams of mAbs. Therefore, we can offer to our customers a wide list of monoclonal antibodies and even the possibility to manufacture their own antibodies in big quantities.

OPERON is glad to offer you the following mAbs that are currently used in many successful tests around the world:

Antigen Clone Isotype Purification Application Other info
Adenovirus Z-2 IgG2a Kappa Protein G LF / ELISA Against hexon protein (genus specific epitope)
Z-64 IgG1 Kappa IEC LF / ELISA
AFP (alpha-fetoprotein) H-14 IgG1 Kappa IEC ELISA Against human alpha-fetoprotein. No cross reaction with HSA
H-15 IgG1 Kappa IEC/HIC ELISA
ALP (Alkaline Phosphatase) C-4 IgG1 Kappa Protein G ELISA The ALP keeps it enzimatic activity in the ALP-mAb complex.
Biotin U-10 IgG1 Kappa Protein G LF / ELISA / MB Against biotin, used as protein or DNA label
Digoxigenin AC-4 IgG1 Kappa IEC ELISA / MB Against digoxigenin, used as protein or DNA label
FITC (Fluorescein isothiocyanate) Y-7 IgM GPC ELISA / MB Against FITC, used as protein or DNA label
IgG Fraction from Y-7 -- --- ELISA / MB
HBsAg (Hepatitis B Virus Surface Antigen) B-7 IgG1 Kappa IEC/HIC ELISA React with Ad and Ay subtypes.
B-15 IgG1 Kappa Protein G LF/ELISA
B-53 IgG2a Kappa IEC/HIC ELISA
B-59 IgG2b Kappa IEC LF / ELISA
B-65 IgG1 Kappa IEC/HIC ELISA
B-65 F(ab´)2 --- --- LF / ELISA
hCG (Human Chorionic gonadotropin) MH-95 IgG1 Kappa IEC/HIC LF / ELISA hCG conformational.Very good cooperation with MH-109
MH-95 F(ab´)2 --- --- LF / ELISA
MH-109 IgG1 Kappa IEC/HIC LF / ELISA Specific to hCG beta subunit. Very good cooperation with MH-95
MH-109 F(ab´)2 --- --- ELISA
Hemocyanin K-6 IgG1 Kappa IEC/HIC LF / ELISA Antibody against hemocyanin from keyhole limpet (KLH)
HRP (Horseradish Peroxidase) S-2 IgG1 IEC ELISA Against horseradish peroxidase
S-9 IgG1 IEC ELISA
Human Hemoglobin N-12 IgG1 Kappa IEC/HIC LF / ELISA Against human Hemoglobin (recognize A0, A2, S and metahemoglobin). Non cross-reaction with bovine, ovine, pig, pigeon, turkey, rabbit and horse hemoglobin
N-14 IgG1 Kappa IEC/HIC LF / ELISA
Human IgM E-6 IgG1 Kappa IEC/HIC ELISA No cross reaction with other human Ig isotypes
Human IgG E-8 IgG1 Kappa IEC/HIC ELISA
Human IgA E-24 IgG2b Kappa IEC/HIC LF / ELISA
Human IgE E-27 IgG1 Kappa IEC ELISA
E-28 IgG1 Kappa IEC/HIC ELISA
E-29 IgG1 Kappa IEC ELISA
p24 HIV (Immunodeficiency virus) P-2 IgG1 Kappa IEC/HIC ELISA Against denatured and soluble p24 from HIV
P-7 IgG1 Lambda IEC/HIC ELISA
P-12 IgG1 Kappa IEC/HIC ELISA
P-16 IgG1 Kappa IEC/HIC ELISA
P-18 IgG1 Kappa IEC/HIC ELISA
P-21 IgG1 Kappa IEC/HIC ELISA
HCV (Hepatitis C virus) O-6 IgG1 Kappa IEC/HIC ELISA Against core protein from HCV
PSA (Prostate Specific Antigen) J-2 IgG1 Kappa IEC/HIC LF / ELISA Recognizes free PSA and PSA-ACT
J-2 F(ab´)2 --- --- LF / ELISA
J-12 IgG1 Kappa Protein G LF / ELISA
J-12 F(ab´)2 --- --- LF / ELISA
Rabit Ig´s F-4 --- IEC ELISA Against rabbit immnoglobulins.
F-7 --- IEC ELISA
Rotavirus W-2 IgG2a Lambda IEC LF / ELISA Against protein capsid
TAMRA AD-12 IgG1 Kappa IEC ELISA / MB Against TAMRA, used as protein or DNA label

*IEC (ion exchange chromatography)

*HIC (Hydrophobic interaction chromatography)

*GPC (Gel permeation chromatography)

*LF (lateral flow)

*MB (Molecular biology)


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